Root > Services > Custom oligo synthesis, DNA and RNA oligos, oligonucleotide modification and labeling services from IBA

A global leader in nucleic acid specialty synthesis since 1991

IBA produces specialized, modified, labor intensive nucleic acid products and oligonucleotides. Our highly motivated and qualified team has a special expertise in custom oligo synthesis, DNA and RNA modification and oligonucleotide labeling.  Our in-house nucleoside and nucleotide chemistry laboratory continuously develops new modifications for DNA and RNA oligos, which are not available elsewhere.

You ask for it – we synthesize it! Just let us know your requirements. 

We provide

  • Custom DNA oligonucleotides up to 200 bases
  • Custom RNA oligos, double stranded RNA (dsRNA), miRNA, small RNA and random RNA synthesis
  • Aptamer custom synthesis
  • Synthetic chimeric oligos
  • Oligonucleotides for Antisense Technology and antisense oligos
  • More than 80 internal, 5’- and 3’- DNA and RNA modifications
  • More than 200 different labels (fluorescent and non-fluorescent dyes, Biotin and Dig) for oligonucleotide labeling
  • The click-chemistry for fast and reliable multiple nucleic acid labeling
  • Real-time PCR (qPCR) and FRET probes
  • More than 100 modified triphosphates (deoxy-, ribo- and α-thio-)
  • RNA and DNA dinucleotides in all combinations


For a brief introduction to our oligo department and a short overview of our products and services please download our borchure World of IBA Oligos.

Quality of products

IBA delivers only highly purified products. We make no compromise in our efforts to reach reproducibly high coupling yields. We have also developed highly sophisticated purification processes to meet the individual needs of each oligonucleotide and modification.

The following points are strictly followed during synthesis of oligonucleotides:

  • Synthesizers from leading manufacturers
  • High quality chemicals from selected suppliers
  • High concentrations of building blocks
  • In-house developed and optimized synthesis cycles
  • Prolonged coupling steps optimized for certain building blocks
  • Purification of oligonucleotides either by HPLC and/or PAGE
  • Two-step purification process for fluorescent probes
  • Exact yield determination by measuring UV-absorption and adjustment of the concentration
  • Routine use of our products for in-house applications like cDNA synthesis, PCR, in vitro transcription, DNA sequencing and gene synthesis

IBA offers free technical assistance provided by nucleic acid chemists and molecular biologists. Take advantage of twenty years of experience in the field of nucleoside-, nucleotide- and oligonucleotide synthesis and application.

Pricing and delivery information

For pricing information you may download the IBA Nucleic Acid price list in EUR und USD.

For our local customers in Göttingen we offer a free-of-charge delivery service directly to your lab!

Our web site special for you! Online orders above EUR 750 [USD 1000] are shipped free of charge! For all other shipments, including orders by e-mail, fax or phone, the price table below applies.


 Room temperature 

Wet ice

Dry ice















European Union







USA, Hawaii, Canada







Switzerland & Norway







Rest of World*







*Invoices (including shipping cost) for North and South America are issued in USD, all other countries not listed separately above  receive invoices (including shipping cost) in EUR.



2. Functional DNA Nanotechnology Workshop - sponsored by IBA!

IBA honors young scientists!

This year’s IBA Young Scientist Award went to 4 participants of the 2. Functional DNA Nanotechnology Workshop in Rome, June, 24 2016!

  • For the verbal presentation: BEST JUNIOR VERBAL PRESENTATION- Guido Grossi (Aarhus University)
  • For the three poster categories:
    • SCHOLAR PRESENTATION- Floris Engelhardt (Technische Universität München) 
    • INNOVATION- Steffen Sparvath (Aarhus University)
    • IMPACT- Wouter Engelen (Eindhoven University of Technology)


More information at

Microsymposium on Small RNA - sponsored by IBA

Once again, IBA sponsors the „Microsymposium on Small RNA Biology“, which is organized by IMBA, IMP, and GMI and the RNA community of the Vienna Biocenter. It brings together young scientists and group leaders from all over the world to discuss their latest findings in the field of small RNAs.

May 2-5, 2016
Vienna, Austria

19th Meeting on T-Cells Subsets and Functions - sponsored by IBA

Marburg, 27 June & 28 June 2016

This meeting covers all recent aspects of T Cell Subsets, including Th1, Th2, Th17, CD8, NKT and regulatory T cells. Further information here.

11. Frühjahrstreffen Transplantationsimmunologie der DGfI - sponsored by IBA

27./28. Mai 2016 in Hannover
Der Workshop soll nicht nur den Mitgliedern des Arbeitskreises, sondern allen Wissenschaftlern, die an Transplantationsfragestellungen interessiert sind, ein Forum zum Informationsaustausch bieten. Es sind Kurzvorträge der Workshopteilnehmer geplant, wobei Beiträge aus allen Forschungsgebieten der Transplantationsimmunologie und -biologie erwünscht sind. Weiterhin soll der Themenkomplex “Novel concepts to modulate immune responses to allo- and xenografts“ in Übersichtsvorträgen diskutiert werden. Weitere Informationen hier.

4th International Biennial Conference on ‘LARPs’ - sponsored by IBA

14 – 17 September 2016, Stockton House, Wiltshire, England

The La related proteins (LARPs) are a family of RNA-binding proteins that are involved in a wide variety of cellular processes including differentiation, development, cell motility, cytoskeleton remodelling and control of transcription and translation. The 2016 international meeting will enable scientists working on La and related proteins from many disciplines to meet and share ideas in an informal setting, thereby facilitating exchanges and collaborations. The scientific programme includes plenary lectures, oral communications selected from submitted abstracts and poster presentations. The talks and presentations will provide an update on the molecular mechanisms that underpin LARP functional regulation of translation, their RNA targets, and the evolution/phylogenetics of these targets.

Frontiers in Medicinal Chemistry-sponsored by IBA

The international symposium will focus on current developments, novel approaches and cutting-edge technologies in the field of medicinal chemistry and drug research with sessions on Target Identification & Lead Discovery, Allosteric Modulators & Modulation of Protein-Protein Interactions, Antibacterial Drugs, Structural Biology, and Highlights in Medicinal Chemistry and Technology. The scientific program will include plenary lectures, short lectures, and poster presentations.
Furthermore, oral communications of (post)doctoral junior scientists will be considered. It is the goal of the organizers to make this meeting an event of scientific excellence, attractive to both industrial and academic scientists in Medicinal Chemistry and related fields of research.

6th Crossroads in Biology (CIB) symposium 2016- sponsored by IBA

The 6th Crossroads in Biology (CIB) symposium 2016 is solely organized by students-members of the Graduate School for Biological Sciences at the University of Cologne.
Students are given the opportunity to show their own research by giving a talk or presenting their work on a poster.
Furthermore small discussion groups will allow students to meet and discuss with the speakers in an informal setting.

10th Microsymposium on Small RNA Biology- sponsored by IBA

The 10th Microsymposium took place at IMBA, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences and IMP, the Research Institute of Molecular Pathology on May 2015, from Monday 4th to Wednesday 6th. The Microsymposium featured a Workshop for PhD students.

Further details here

The "Journées du Campus d'Illkirch" sponsored by IBA

The "Journées du Campus d'Illkirch" take place on 13 and 14 April 2015. This event offers to the participating research units an opportunity to present their current work and researchers of this campus have a chance to learn more about research carried out in nearby laboratories and good reasons to meet together!

Gold medal at BIOMOD 2014

At the BIOMOD 2014 competition, Wyss Institute in Harvard, students from the group of Prof. Dr. Tinnefeld, TU Braunschweig, Germany, won a gold medal for the “Nanoscooter”, a nanoscale car consisting of DNA. Also for their suit the won the prize for the best T-shirt. BIOMOD is an annual biomolecular design competition for students. See also

IBA GmbH has established “Young Scientist Sponsorships” for attending retreats, meetings or conferences.

Dr. Thomas Lavergne (CNRS GRENOBLE, France) and Dr. Joachim Bertram (IBA GmbH, Göttingen) at the 16. SCNAC 2014



  • Dr. Thomas Lavergne, CNRS GRENOBLE, France. 1st "Gänse-Liesel" conference fee for young scientists for speakers of the 16th Symposium on Chemistry of Nucleic Acid Components (16. SCNAC) in the Czech Republic
  • Dr. Michael Schmück, Charité - Universitätsmedizin Berlin, Germany. Conference fee for the ISCT 2014 Annual Meeting in Paris, France


  • Students´ Retreat of the Harvard Virology Program, Harvard Medical School, Boston, USA