Home > News > IBA GmbH has started a joint project together with the Institute for Technical Chemistry (TCI) in Hannover and the LIMES Institute at the University of Bonn

IBA GmbH has started a joint project together with the Institute for Technical Chemistry (TCI) in Hannover and the LIMES Institute at the University of Bonn

IBA GmbH, Goettingen has entered into cooperation with the research groups of Prof. Cornelia Blume at TCI and Prof. G. Mayer at LIMES in 2019. This joint project is supported by a project grant from the AiF, Berlin. The project is aiming at developing APTAMER-based tools and detection kits using IBA’s more than 20 years of expertise in oligonucleotide and APTAMER synthesis. The APTAMER-based kits will be developed for early detection of transplant rejection focusing on kidney transplantation first.

Based on the longstanding experience of Prof. Mayer’s group in APTAMER development and application, specifically in generating chemically modified APTAMERs to be used as capturing reagents (as well known for antibody-antigen interactions) we seek to identify suitable APTAMERs recognizing specific T-cell markers predictive for kidney transplant rejection. The group of Prof. Blume has extended knowledge in the field of kidney transplantation and transplant rejection issues as well as in assay development like ELONA assays for point-of-care (POC) diagnostics, which will help to develop a robust and sensitive POC test for the intended early detection of kidney rejection problems as early as possible in transplanted patients.

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