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IBA GmbH – Solutions for Life Sciences

For more than two decades IBA provides innovative technologies for the life sciences applications. Including tools for cell selection & expansion, protein production & assays and custom oligos & predefined DNA/RNA.

Cell selection & expansion

Automated cell selection via the Fab-TACS® technology directly from whole blood is possible using IBA’s design award winning FABian® device. Customized protocols depending on the cell type, the sample volume and the intended yield for the cell type of interest allow a convenient fully automatic cell isolation. Strep-tagged Fab fragments (Fab-Streps®) reversibly capture and release the target cells during the selection process. This delivers label-free, non-activated target cells in a standardized manner of highly reproducible quality. Isolated cells are suitable for all further immunologic or cell biologic investigations including cell based diagnostics or assays, e.g. pharmacological analysis of drug levels in the isolated cell fraction. Alternatively to FABian® we offer gravity flow columns for manual cells selection based on the same technology. For T cell stimulation, we offer completely novel reversible reagents, the Streptamers® for cell expansion, which provide unique flexibility for cell research.

Protein production & assays

The Strep-tag® technology is IBA's proprietary and versatile protein purification, detection and immobilization platform. It is one of the most widely used systems for affinity purification that provides exceptional pure proteins. Recently the third generation of the Strep-tag system was launched based on the new Strep-Tactin®XT and Twin-Strep-tag®. Strep-Tactin®XT is a further developed Strep-Tactin® with extra tight binding to Twin-Strep-tag® now enabling the usage of the Strep-tag® technology in applications where extra tight binding is a requirement. Thereby the third generation Strep-tag® technology now enters the field of assay development and screening. This opens new possibilities in the pharmaceutical and biotech sector for, e.g. screening of new diagnostic targets and the development of diagnostic assays.

Custom Oligos & Predefined DNA/RNA

IBA’s nucleic acid division has a focus on specialized nucleic acid custom services. The tailor-made DNA and RNA oligonucleotides, including modified and labeled nucleic acids, require particular care in synthesis and are of the highest quality. Applications can be found in e.g. real-time PCR, FRET, gene silencing studies, immobilization, FCCS or high resolution microscopy. The innovative Click Chemistry enables additional dye combinations with unsurpassed labeling densities. More than 200 fluorescent labels and more than 80 modifications are available. With our expertise, we can also produce custom DNA and RNA aptamers according to your individual specifications.

IBA Team

Dr. Mike Rothe

CEO - Dr. Mike Rothe
Managing Director, Chief Executive Officer
Mike Rothe has extensive biotech industry experience and expertise in building successful life science companies. His involvement in biotechnology started as a visiting scientist at Genentech, Inc. (South San Francisco, USA) in 1992. From 1994 to early 1999, he was a Staff Scientist and Team Leader at Tularik, Inc. (South San Francisco, USA). In 1999, Dr. Rothe joined DeveloGen AG (Göttingen, Germany) as Vice President, Research and Development and later served as its Chief Scientific Officer. In July 2001, he co-founded U3 Pharma AG (Munich, Germany) and assumed the roles of Managing Director and CSO. He was instrumental in the acquisition of U3 Pharma by Daiichi Sankyo in 2008. From 2009 to 2012 he served as CEO and Member of the Board of Directors of Igenica, Inc. (Burlingame, USA). Prior to joining IBA GmbH, he was CEO of ImmunoQure AG (Munich, Germany) and CEO and Delegate of the Board of Directors of ImmunoQure Research AG (Zurich, Switzerland). Dr. Rothe studied biochemistry at the University of Tübingen before receiving his Ph.D. from the University of Munich and being awarded the Otto-Hahn Medal of the Max-Planck-Society. He is the author of numerous scientific articles and international patents.

Dr. Joachim Bertram

CSO - Dr. Joachim Bertram

Managing Director, Chief Scientific Officer
Joachim Bertram received his Ph.D. in microbiology in the department of Prof. Gottschalk at the University of Goettingen. Then he moved to the department of hematology and oncology headed by Prof. Hiddemann where he has held a number of positions of increasing seniority in the biomedical profession. He conducted scientific and applied research on the use of antisense oligonucleotides and ribozymes in the field of proliferative diseases. In addition he focussed on mechanisms of drug resistance development and the use of nucleic acid based compounds for growth factor mimicry. In 1998, Joachim Bertram finished his "habilitation" in the medical faculty. He joined IBA GmbH in January 2000 and became CEO of IBA Biologics in 2001.

Dr. Herbert Stadler

Dr. Herbert Stadler

Head of the Advisory Board
Over the last two decades, Herbert Stadler has built a track record as one of Germany's most active biotech entrepreneurs. He has founded or co founded several companies including Biometra GmbH, Ribonetics GmbH, HepaVec AG, IBA GmbH and DeveloGen AG. Herbert Stadler is a neurochemist by training. He obtained his Ph.D. at the Freie University of Berlin, obtained his postdoctoral lecture qualification ("Habilitation") at the University of Göttingen and headed the Molecular Neurobiology Group at the Max-Planck Institute of Biophysical Chemistry in Göttingen. He currently serves on the supervisory boards of DeveloGen AG and IBA GmbH. 

Cell selection & expansion

Dr. Herbert Stadler

Protein production & assays

Dr. Uwe D. Carl

Custom oligos & predefined DNA/RNA

Marc Niwar

Marketing & sales

Dr. Wolf Jockusch

General contact information

Phone +49 (0) 551 50672-0
Fax +49 (0) 551 50672-181
E-mail info@iba-lifesciences.com

Innovation Award 2015 – Pioneer work in developing rapid diagnostic tests
This year 101 participants applied for the 13th Innovation Prize of the county Göttingen. IBA was nominated together with the Fassisi GmbH for the joint project in the category “candidates with more than 20 employees”. Among the 29 nominees, the diagnostic test for veterinary diseases of IBA and Fassisi was choosen as one of the top five innovations.
Veteri-nost® is a prototype and represents a rapid and cost-effective device. It is based on IBA’s Strep-tag®/Strep-Tactin® technology that is used as standardized diagnostic tool. The analysis is similar to a pregnancy test. A test strip changes the color if disease related proteins are present.
For the measurement, blood or other body fluids are used to determine pathological changes.
Dr. Joachim Bertram, the managing director of IBA, states: “This technology sets a new benchmark for rapid diagnostic tests. The procedures can be applied to various antigens. Similar to a puzzle, one part of the system can easily be exchanged so that a different pathogen is detected. This is completely new and pioneering.”
A movie introducing our innovation is available on YouTube:
6th Foreign Trade Award of Lower Saxony

The Minister of Economics of Lower Saxony, Olaf Lies, granted the 6th Trade Award in the capital city Hanover. In the category small and medium-sized businesses IBA GmbH was nominated as one of the top five companies. This award appreciates the export-oriented German industry and honored innovative companies who have asserted themselves in the international export market.  Dr. Joachim Bertram and Dr. Thomas Schmidt, both managing directors of IBA, received the prize at the trade fair in Hanover on 15 April 2015 and felt much honored to be under the first ones of totally 69 companies applied for this award.

More information and the complete press release of the award ceremony here: http://www.mw.niedersachsen.de/aktuelles/presseinformationen/minister-olaf-lies-verleiht-auenwirtschaftspreis--132900.html

ISO 9001:2008 Quality Management Standard certification

Being the most recognized quality management standard in the world, ISO 9001:2008 is designed to help organizations to ensure that they meet the needs of customers and employees. It recognizes that the policies, practices and procedures of a company consistently result in high quality products and services which are provided to their customers.

Dr. Joachim Bertram, Managing Director at IBA, discusses receipt of the certificate: “Since 2004, IBA’s production and customer service fulfilled the high level of the ISO demands and standard procedures. However, gaining this accreditation now enables us to really demonstrate and highlight our high quality performance to our customers”.

IBA GmbH is dedicated to providing high quality tools for life science research and supports customers from early discovery to commercialization in industry and academia. The company offers solutions for the entire production chain of recombinant proteins, from oligonucleotide custom synthesis, cloning, transfection, protein expression and purification, to detection, immobilization and assays. We also deliver new tools for immunology research, including a growing line of tag-based reagents for cell isolation.

Innovation Award 2011 for the unique Streptamer® technology
In recognition of the innovative Streptamer® technology IBA was granted this local award.

For more information please watch the Streptamer® video (in German).

Sponsorships

2. Functional DNA Nanotechnology Workshop - sponsored by IBA!

IBA honors young scientists!

This year’s IBA Young Scientist Award went to 4 participants of the 2. Functional DNA Nanotechnology Workshop in Rome, June, 24 2016!

  • For the verbal presentation: BEST JUNIOR VERBAL PRESENTATION- Guido Grossi (Aarhus University)
  • For the three poster categories:
    • SCHOLAR PRESENTATION- Floris Engelhardt (Technische Universität München) 
    • INNOVATION- Steffen Sparvath (Aarhus University)
    • IMPACT- Wouter Engelen (Eindhoven University of Technology)

Congratulations!

More information at http://www.fdn2016.com/awards/.

Microsymposium on Small RNA - sponsored by IBA

Once again, IBA sponsors the „Microsymposium on Small RNA Biology“, which is organized by IMBA, IMP, and GMI and the RNA community of the Vienna Biocenter. It brings together young scientists and group leaders from all over the world to discuss their latest findings in the field of small RNAs.

May 2-5, 2016, Vienna, Austria

19th Meeting on T-Cells Subsets and Functions - sponsored by IBA

Marburg, 27 June & 28 June 2016

This meeting covers all recent aspects of T Cell Subsets, including Th1, Th2, Th17, CD8, NKT and regulatory T cells. Further information here.

11. Frühjahrstreffen Transplantationsimmunologie der DGfI - sponsored by IBA

27./28. Mai 2016 in Hannover
 
Der Workshop soll nicht nur den Mitgliedern des Arbeitskreises, sondern allen Wissenschaftlern, die an Transplantationsfragestellungen interessiert sind, ein Forum zum Informationsaustausch bieten. Es sind Kurzvorträge der Workshopteilnehmer geplant, wobei Beiträge aus allen Forschungsgebieten der Transplantationsimmunologie und -biologie erwünscht sind. Weiterhin soll der Themenkomplex “Novel concepts to modulate immune responses to allo- and xenografts“ in Übersichtsvorträgen diskutiert werden. Weitere Informationen hier.
 

4th International Biennial Conference on ‘LARPs’ - sponsored by IBA

14 – 17 September 2016, Stockton House, Wiltshire, England
The La related proteins (LARPs) are a family of RNA-binding proteins that are involved in a wide variety of cellular processes including differentiation, development, cell motility, cytoskeleton remodelling and control of transcription and translation. The 2016 international meeting will enable scientists working on La and related proteins from many disciplines to meet and share ideas in an informal setting, thereby facilitating exchanges and collaborations. The scientific programme includes plenary lectures, oral communications selected from submitted abstracts and poster presentations. The talks and presentations will provide an update on the molecular mechanisms that underpin LARP functional regulation of translation, their RNA targets, and the evolution/phylogenetics of these targets.

Frontiers in Medicinal Chemistry-sponsored by IBA

 
The international symposium will focus on current developments, novel approaches and cutting-edge technologies in the field of medicinal chemistry and drug research with sessions on Target Identification & Lead Discovery, Allosteric Modulators & Modulation of Protein-Protein Interactions, Antibacterial Drugs, Structural Biology, and Highlights in Medicinal Chemistry and Technology. The scientific program will include plenary lectures, short lectures, and poster presentations.
Furthermore, oral communications of (post)doctoral junior scientists will be considered. It is the goal of the organizers to make this meeting an event of scientific excellence, attractive to both industrial and academic scientists in Medicinal Chemistry and related fields of research.
 

6th Crossroads in Biology (CIB) symposium 2016- sponsored by IBA

The 6th Crossroads in Biology (CIB) symposium 2016 is solely organized by students-members of the Graduate School for Biological Sciences at the University of Cologne.
Students are given the opportunity to show their own research by giving a talk or presenting their work on a poster.
Furthermore small discussion groups will allow students to meet and discuss with the speakers in an informal setting.

10th Microsymposium on Small RNA Biology- sponsored by IBA

The 10th Microsymposium took place at IMBA, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences and IMP, the Research Institute of Molecular Pathology on May 2015, from Monday 4th to Wednesday 6th. The Microsymposium featured a Workshop for PhD students.

Further details here http://www.imba.oeaw.ac.at/microsymposium

The "Journées du Campus d'Illkirch" sponsored by IBA

The "Journées du Campus d'Illkirch" take place on 13 and 14 April 2015. This event offers to the participating research units an opportunity to present their current work and researchers of this campus have a chance to learn more about research carried out in nearby laboratories and good reasons to meet together!

Gold medal at BIOMOD 2014

At the BIOMOD 2014 competition, Wyss Institute in Harvard, students from the group of Prof. Dr. Tinnefeld, TU Braunschweig, Germany, won a gold medal for the “Nanoscooter”, a nanoscale car consisting of DNA. Also for their suit the won the prize for the best T-shirt. BIOMOD is an annual biomolecular design competition for students. See also http://openwetware.org/wiki/Biomod/2014/Braunschweig.

IBA GmbH has established “Young Scientist Sponsorships” for attending retreats, meetings or conferences.

 

Sponsorships:

2014

  • Dr. Thomas Lavergne, CNRS GRENOBLE, France. 1st "Gänse-Liesel" conference fee for young scientists for speakers of the 16th Symposium on Chemistry of Nucleic Acid Components (16. SCNAC) in the Czech Republic
  • Dr. Michael Schmück, Charité - Universitätsmedizin Berlin, Germany. Conference fee for the ISCT 2014 Annual Meeting in Paris, France

2013

  • Students´ Retreat of the Harvard Virology Program, Harvard Medical School, Boston, USA