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Strep-Tactin® Magnetic Microbeads

Strep-Tactin® multimers conjugated with magnetic microbeads
Quantity Unit price
From 10
Strep-Tactin® Magnetic Microbeads are microspheres covalently linked to Strep-Tactin®. They are suitable for labeling antigen-specific cytotoxic T cells (MHC I Streptamer®) or surface marker-specific cells (Fab-TACS®/Nano-TACS®). To target specific cells, MHC I complexes, low affinity Fab fragments or nanobodies fused to a Twin-Strep-tag® (MHC I-Streps, Fab-Streps or Nano-Streps) are required in addition to fluorescent Strep-Tactin®. Strep-Tactin® multimerizes MHC I-Streps or Fab-/Nano-Streps, ensuring stable binding to cells. The resulting magnetic complexes can be used to label cells that are specific for the respective peptide-loaded MHC I molecule or for a selected surface marker. The addition of biotin reverses the multimerization and causes the dissociation of MHC I-Streps or Fab-/Nano-Streps from the cell surface. The complete removal of all labeling reagents permits serial positive selection as well as depletion steps and reserves the cells’ full biological activity.


Bead Size: 1 - 3 µm
Form: Suspension in DPBS
Possible Application: Cell isolation (magnetic)
Recommended Usage: 15 µl per 1 x 10^7 total cells

Shipping information

Storage: 2-8 °C; Do not freeze!
Stability: 6 months after shipping
Shipping: Room temperature


StrepMan Magnet
Permanent magnet for cell isolations using Strep-Tactin® Magnetic Microbeads
10x Buffer CI
Cell isolation buffer containing 10x PBS with 10 mM EDTA and 5% BSA
MHC I-Strep HLA-A*0201; CMV pp65 (NLVPMVATV)
MHC class I molecule fused to a Twin-Strep-tag® and refolded with a peptide
MHC class I molecule fused to a Twin-Strep-tag® and refolded with a peptide

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