MagStrep "type3" XT beads




Magnetic Strep-tag® purification at its best! - A superior tool for small scale batch purification with high demands on protein purity.

Magnetic beads are a common tool to isolate proteins or complexes via a pull-down, immunoprecipitation (IP) or co-immunoprecipitation (Co-IP). The advantage of a magnetic beads based pull-down/IP is the simple and reproducible handling of the product. Due to the magnetic core of the beads no centrifugation step is required any more, the beads can be easily separated with a magnetic separator and the risk of disturbing the pellet or loss of beads within the wash step is close to zero.

 MagStrep “type3” XT beads are Strep-Tactin®XT coated magnetic beads with the following characteristics:

  • high binding capacity (up to 0.85 nmol/μl beads, corresponding to 30 μg of a 30 kDa protein)
  • very low non-specific protein binding due to an improved coating
  • flexible elution conditions (under denaturing conditions by boiling in SDS gel loading buffer or under native conditions with biotin)
  • high affinity for Twin-Strep-tag® – due to new Strep-Tactin®XT

These characteristics lead to very good purification results. MagStrep “type3” XT magnetic beads are therefore a convenient tool for small-scale purifications with high demands on binding specificity as required in pull-down assays and high-throughput screenings.

Product Contents Price   Order
10x Buffer W 100 ml 2-1003-100 USD 45.00  

Strep-Tactin®/Strep-Tactin®XT Wash Buffer is used for the removal of unbound molecules from immobilized Strep-Tactin® and Strep-Tactin®XT during Strep-tag® protein purification.

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Biotin 2 g 2-1016-002 USD 78.00  

Biotin is a water-soluble B-complex vitamin (vitamin B7 or vitamin H) ...

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Biotin 5 g 2-1016-005 USD 169.00

Biotin is a water-soluble B-complex vitamin (vitamin B7 or vitamin H) ...

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10x Buffer BXT 25 ml 2-1042-025 USD 66.00  

Buffer BXT is a Strep-Tactin®XT Elution Buffer with Biotin. It contains a Biotin concentration for competitive displacement of purified recombinant Strep-tag®II or Twin-Strep-tag® fusion proteins from immobilized Strep-Tactin®XT. ...

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Magnetic Separator 1 piece 2-1602-000 USD 239.00  

Magnetic separator (for 24 reaction tubes, 12x 1.5 ml and 12x 2 ml) for the fast purification of Strep-tag® proteins with MagStrep "type3" XT beads (Strep-Tactin®XT coated magnetic beads) in batch format. Within minutes, the target molecules are bound specifically by Strep-Tactin®XT. Using the magnetic separator, the magnetic beads are separated within seconds from solution.

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MagStrep "type3" XT beads 2 ml 2-4090-002 USD 212.00
MagStrep "type3" XT beads 10 ml 2-4090-010 USD 736.00



See where to use MagStrep “type 3” XT beads!

  • Protein purification

Essuman K, Summers DW, Sasaki Y, Mao X, Yim AKY, DiAntonio A, Milbrandt J. (2018) TIR Domain Proteins Are an Ancient Family of NAD+ -Consuming Enzymes. Curr Biol. 28(3): 421-430 [Link]

Zhang Y, Ptacin JL, Fischer EC, Aerni HR, Caffaro CE, San Jose K, Feldman AW, Turner CR, Romesberg FE. (2017) A semi-synthetic organism that stores and retrieves increased genetic information. Nature. 551(7682): 644-647. [Link]

  • Pull-down assay

González M, Brito N, González C. (2017) The Botrytis cinerea elicitor protein BcIEB1 interacts with the tobacco PR5-family protein osmotin and protects the fungus against its antifungal activity. New Phytol. 215(1): 397-410. [Link]

Jeong, S. J., Park, S., Nguyen, L. T., Hwang, J., Lee, E. Y., Giong, H. K., ... & Kim, H. K. (2019). A threonyl-tRNA synthetase-mediated translation initiation machinery. Nature Communications10(1), 1357.[Link]

Maidorn, M., Olichon, A., Rizzoli, S. O., & Opazo, F. (2019). Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons. In MAbs (Vol. 11, No. 2, pp. 305-321). Taylor & Francis. [Link]

  • RNA co-immunoprecipitation

Chen Z, Mashburn-Warren L, Merritt J, Federle MJ, Kreth J. (2017) Interference of a speB 5' untranslated region partial deletion with mRNA degradation in Streptococcus pyogenes. Mol Oral Microbiol. 32(5): 390-403. [Link]